Synthesis of 1-tert-Alkyl-6, 7-dimethoxyisoquinolines.
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چکیده
منابع مشابه
Isoquinoline Promoted Synthesis of alkyl 2-(1-alkyl-5-oxo-3-phenyl-2-thioxotetrahydro-4H-imidazol-4-yliden) acetate derivatives
Derivatives of thiazolidinone ring systems are known to act as anti-HIV infections , analgesic, anti-bacterial, anti-convulsant, anti parasitic, potential anti-inflammatory and herbicidal agents. Due biological activities of thiazolidinones ring, several methods for their synthesis have been illustrated in literature. Imidazolidine-2-thiones were synthesized by the oxidative cyclization of 1-be...
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The synthesis of sterically hindered amines has been a significant challenge in organic chemistry. Herein, we report a modular, three-component coupling that constructs two carbon-nitrogen bonds including a sterically hindered Csp3-N bond using commercially available materials. This process uses an earth-abundant copper catalyst and mild reaction conditions, allowing access to a variety of comp...
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The palladium-catalyzed coupling reaction of 6-iodoisoflavone, prepared from 3'-iodoacetophenone derivative, with 2-methyl-3-butyn-2-ol gave 6-alkynylisoflavone derivative, which was hydrogenated to give 6-alkylhydroxyisoflavone (luteone hydrate) (2). Dehydration of 2 gave 2',4',5,7-tetrahydroxy-6-prenylisoflavone (luteone) (1). Wighteone hydrate (3) was also synthesized from 6-iodotris(benzylo...
متن کاملThe Molecular Structure of 1 , 3 , 5 , 7 - Tetra ( tert - butyl ) - 2 , 4 , 6 , 8 - tetra ( chloro ) - borazocine [ 1 ]
The borazocine (ClB=NCMe3)4 crystallizes in the monoclinic system, space groupC2/c with Z = 6, i. e. there are two independent molecules in the unit cell. The first molecule has no crystallographic symmetry, while the second molecule is characterized by a twofold axis which generates the (ClB= NCMe3)4 molecule from the fragment (ClB=NCMe3)2. The molecules are tub-shaped showing alternating long...
متن کاملThe Molecular Structure of 1 , 3 , 5 , 7 - Tetra ( tert - butyl ) - 2 , 4 , 6 , 8 - tetraazido - borazocine [ 1 ]
The tetra(tert-butyl)-tetraazido-borazocine, 1, has the expected tub shape as determined for (SCNB=NtBu)4. However, it crystallizes in the triclinic system and shows no symmetry element in contrast to the isothiocyanato derivate which has C2 symmetry. There are two kinds of BN bonds which alter from long to short (average 1.491 and 1.388 Å). The BN bond lengths to the azido groups are, on avera...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1958
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.6.186